Artificial sweeteners are associated with long-term weight gain and diseases like increased risk of obesity, diabetes, high blood pressure and heart disease. Consumption of artificial sweeteners, like as aspartame and sucralose, is widespread and increasing. Emerging data solely indicate that or nonnutritive, artificial sweeteners may have negative effects on metabolism, gut bacteria and appetite, although the evidence is conflicting.
The tests and procedures does not show a consistent effect of artificial sweeteners on weight loss, and the longer observational studies provokes a link between consumption of artificial sweeteners and increased risks of weight gain and obesity, high blood pressure, diabetes, heart disease and other health issues. Overweight and obesity is associated with a higher risk of cardiovascular disease and it is recommended to lose weight likewise through the physical activity is associated with a lower risk of cardiovascular disease regardless of age. The researchers analysed the joint effect of physical activity and BMI (Body Mass Index), Compared to normal weight people with high physical activity level, overweight or obese patients with high levels of physical activity were not at increased risk of cardiovascular disease, but overweight people with low levels of physical activity had 1.33 and 1.35 times higher risk for developing cardiovascular disease, respectively.
Overweight and other health related issues exert harmful effects through adipose tissue which accelerates the atherosclerotic process and increases cardiovascular risk. Moreover physical activity lowers the harmful effects of atherosclerosis by reducing the stabilization of plaques on blood vessels and reducing the heart's oxygen demand. People with high levels of physical activity are protected from the harmful effects of adipose tissue on cardiovascular disease.
As a result widespread and increasing use of artificial sweeteners and the current epidemic of obesity and related diseases, more research are needed to determine the long-term risks and benefits of these products.
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